Effects of interacting variables on the tensile strength and the release properties of paracetamol tablets

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Effects of interacting variables on the tensile strength and the release properties of paracetamol tablets

Purpose: The individual and interaction effects of nature of binder (N), concentration of binder (C) and the relative density (D) on the tensile strength and release properties of paracetamol tablets have been studied using a 2 factorial experimental design. Methodology: Khaya gum, which represented the “low” level, and polyvinylpyrrolidone (PVP), which represented the “high” level, was used as...

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Influence of process variables on release properties of paracetamol tablets.

A 2(3) factorial experimental design has been used to quantitatively study individual and interaction effects of the nature of binder (N), binder concentration (c) and relative density of tablet (d) on the disintegration time (DT) and dissolution times, t1, t50 and t90, of paracetamol tablet formulations. The factorial design was also used to study the quantitative effects of pregelatinization ...

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ژورنال

عنوان ژورنال: Tropical Journal of Pharmaceutical Research

سال: 2003

ISSN: 1596-9827,1596-5996

DOI: 10.4314/tjpr.v2i1.14579